Src 10 ug

Code: 23-042 D2-231

General description

Src is a ubiquitously expressed, non-receptor tyrosine kinase that plays a pivotal role in numerous cellular processes such as proliferation, migration, a...


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€726.80 EACH
€893.96 inc. VAT

General description

Src is a ubiquitously expressed, non-receptor tyrosine kinase that plays a pivotal role in numerous cellular processes such as proliferation, migration, and transformation. Due to its critical function in regulating signal transduction pathways, Src activity is tightly controlled through reversible phosphorylation and dephosphorylation events and down-regulation by ubiquitin-dependent degradation. Dysfunction of Src, through overexpression or increased activation has profound effects on basic cellular functions. Elevated Src expression and/or activation is evident across a wide range of solid tumour types and has been strongly implicated in the development, maintenance, progression, and metastatic spread of several human cancers, such as prostate, lung, breast, and colorectal cancer.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

biological sourcehuman
manufacturer/tradenameUpstate®
NCBI accession no.NM_198291
Quality Level300, 100
recombinantexpressed in baculovirus infected Sf21 cells
technique(s)activity assay: suitable
This product has met the following criteria to qualify for the following awards:



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